DESPITE the increasing success of conventional medical therapeutic approaches and continued development and improvement of mechanical revascularisation approaches, a significant number of angina and coronary heart disease patients cannot be managed successfully. Also a substantial proportion of these patients do not achieve complete revascularisation even after successful angioplasty/bypass surgery and continue to experience exertional angina or ischemia despite medication. Apart from these factors, the traditional procedures - bypass surgery (CABG) and angioplasty (PTCA) - are expensive and involve a certain degree of risk in the form of iatrogenic morbidity and mortality. More...
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